furosemide (Lasix®)
Loop diuretic
Furosemide is a potent diuretic that inhibits the reabsorption of sodium and chloride in the proximal tubule and loop of Henle.
Diuretic effects within 15-20 minutes, vasodilatory effects within 5 minutes when given IV.
4-6 hours
Cardiogenic pulmonary edema
Congestive heart failure
Anuria
Hypersensitivity
Hypovolemia/dehydration
Known hypersensitivity to sulfonamides
States of severe electrolyte depletions
Hypotension
Dry mouth
Hypochloremia
Hypokalemia
Hyponatremia
Hyperglycemia
Tinitus if given too rapidly.
Digitalis toxicity may be potentiated due to potassium depletion, which can result from furosemide administration.
Lithium toxicity may be potentiate due to sodium depletion.
10mg/ml in 2 ml ampule, 10 mg/ml in 10 ml vial
20-40 mg (0.5-1.0 mg/kg) slow IV over 1-2 minutes (not to exceed 20mg/min) or twice the patient's daily oral dose.
1mg/kg/dose
Pregnancy Safety: Category C
Furosemide has been known to cause fetal abnormalities
Should be protected from light