Name

activated charcoal

Class

Adsorbent

Description

Activated charcoal is a fine black powder that binds and adsorbs some specific ingested toxins that may still be present in the GI tract following emesis. Once bound to the activated charcoal, the combined complex is excreted from the body.

Onset

Immediate

Duration

Continual while in the GI tract

Indications

Many ingested poisonings.

Contraindications

Corrosives, caustics, or petroleum distillates (relatively ineffective, and may induce vomiting).

Adverse Reactions

May indirectly induce nausea and vomiting. May cause constipation.

Drug Interactions

Syrup of ipecac is adsorbed by activated charcoal.

Supplied

25 g (black powder)/125 ml bottle (200 mg/ml)

50 g (black powder)/250 ml bottle (200 mg/ml)

Dose/Administration

Approximately 1-2 g/kg body weight (larger amounts if food is also present), prepared in a slurry and administered PO or slowly by gastric tube.

Adult

1-2 g/kg

Pediatric

15-30 g

Special Considerations

Pregnancy Safety: not established

Activated charcoal may also be known as "AC"

Is relatively insoluble in water

May blacken feces

Must be stored in a closed container.

Different charcoal preparations may have varying rates of adsoprtion

Does not adsorb all drugs and toxic substances (for example, cyanide, lithium, iron, lead, and arsenic)

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